News

MassVentures START Funds Give Kytopen an Early Boost

MassVentures awarded Kytopen a “Stage I” $100,000 grant through our Small Business Innovation Research (SBIR) Targeted Technologies (START) program in 2019. The funding allowed the Kytopen team to sell their product by attending conferences, trade shows, and working with partners to scale up production. While such activities are critical for startups seeking to raise capital and grow, SBIR grants don’t cover those expenses …

Rapid discovery and manufacture of next-generation cell therapies

MIT spin-out company Kytopen has engaged Cambridge Consultants to co-develop the first Flowfect™ system. Flowfect™ is a scalable, gentle process that yields billions of high-quality engineered cells in minutes. The system will streamline the engineering of a wide array of human and human-derived cells for use in next-generation …

Flowfect™ Tx Revealed

The Flowfect™ Tx System features an automated, single use closed system for maximum ease of use and flexibility. This non-viral delivery technology uses continuous fluid flow combined with electric fields for high efficiency delivery of payloads such as mRNA, DNA, and CRISPR RNP complexes. The Flowfect™ technology is compatible with a variety of cells, including iPSCs, primary T cells, and other human hematopoietic …

Technology Startup Kytopen Raises $3.6 Million Seed Round

“In the short time since The Engine’s first investment, Kytopen has made significant progress in developing a platform that is demonstrably faster, more efficient and more scalable than traditional methods,” said Katie Rae, CEO and managing partner of The Engine…

Breaking the Bottleneck in Genetic Engineering

Building on expertise devising microfluidics tools for use in small-scale biological systems, Buie’s lab invented a tiny pipette equipped with electrodes through which cells flow. As cells move through the pipette’s tiny channel, they are exposed to an electric field with just the right amount of current to open their pores. “So now we can continuously …